Spermidine got its name from its discovery in semen. The term ‘spermidine’ was coined in 1928 by a researcher named S. Windaus, and it comes from the Greek word ‘sperma’ (meaning seed) and ‘amino’ (indicating its amino acid nature). While it was initially found in semen, it is now known to be present in various bodily tissues and foods.
While the fountain of youth remains elusive, spermidine is a supplement recently launched that is believed to promote cellular longevity. With its ability to aid cell growth, being fundamental to tissue repair and maintenance, and its capacity in DNA stabilisation, it can prevent cellular decline, and aid the production of new cells.
Its physiological improvements extend to brain health, protecting the neuro system through a reduction in oxidative stress as well as promoting the survival of neurons. This improvement brain health directly benefits cognitive function, improving cognitive performance and mental clarity.
Spermidine is a naturally occurring polyamine, an organic compound characterised by the presence of multiple amino groups. It is found in various biological tissues, including human cells and certain foods, and supports various essential physiological processes.
Spermidine serves several critical functions in the human body, including:
Nick Wignall of Very Well Mind
writes about this often, and there are some words he uses regularly which I now remind myself of often –
“Anxiety is usually caused by the worry of feeling anxious, than anxiety itself”.
Given its diverse functions in the body, spermidine has become a popular supplement in biohacking and neuroscience communities.
Benefits of spermidine supplements include:
Cell growth and division are fundamental processes that play a critical role in the overall health and function of the human body. These processes are essential for several key reasons:
In essence, the precise control of cell growth and division is crucial for overall health, tissue repair, immune function, and the development of an individual from a single cell into a complex, multicellular organism. Without these processes, life as we know it would not be possible.
Supplements that support the process of cell growth and division are a key development in biohacking communities, as they aid the essential physiological processes happening within us at a cellular level.
DNA stability is the bedrock of genetic information, ensuring that genetic material is faithfully replicated, maintained, and protected. This stability is crucial for the normal development, growth, and health of an organism and for the preservation of species across generations.
DNA stability is, therefore, a cornerstone of life itself, safeguarding the blueprint of all living organisms.
It affects the body in the following ways:
Autophagy is a vital cellular process that plays a pivotal role in maintaining overall health and wellbeing. It’s a highly regulated process that involves the breakdown and recycling of damaged or unnecessary cellular components.
Autophagy is involved in the following activities in the body:
In essence, autophagy is a dynamic and finely tuned process that contributes to cellular health, adaptation, and overall survival. It is involved in numerous physiological functions, from maintaining cellular cleanliness to supporting longevity and disease prevention. Research into the regulation and manipulation of autophagy holds great promise for understanding and improving human health and well-being.
Spermidine is considered to benefit brain health in several ways:
Latest Outcomes and Conclusions by Scientists
Recent studies have yielded promising findings regarding the effects of spermidine on brain health. A study published in the journal ‘Nature Medicine’ in 2019 demonstrated that spermidine supplementation in mice led to improved memory and cognitive function.
Researchers observed reduced age-related brain atrophy and neuroinflammation, indicating spermidine slows age-related cognitive decline.
Another study published in ‘Nature Communications’ in 2020 examined the potential neuroprotective effects of spermidine in a fruit fly model of Alzheimer’s disease. The results indicated that spermidine administration reduced the accumulation of toxic protein aggregates associated with Alzheimer’s.
Spermidine is believed to contribute to longevity in several ways:
As well as being available in supplement form, spermidine can also be naturally boosted within the body.
It’s beneficial to always include a mix of natural alternatives alongside supplements to include the additional benefits that come with a combined approach to biohacking.
Below are the supplementary ways to promote endogenous spermidine production:
While spermidine supplements offer numerous potential benefits, they are new to market and so risks need to be considered:
We are living in a world where science and technology are chasing the answer to eternal youth, with a market of USD 64 B in 2023, and expected to grow to USD 109.8 B by 2033.
With entrepreneurs chasing the illusive fountain of eternal youth, it is only time before we find the way to prevent aging. Which feels like a very scary idea – the thought of a never aging population, with a rapid increase in global population. The risks are not worth thinking about.
But while the elixir remains just out of grasp of us all, the anti-aging supplement market will continue to provide us with products that help improve the health of our bodies at a physiological level; ensuring our cellular procedures are optimised for a life of longevity and long-term cognitive function.
Spermidine is one of the products we’re excited about, and look forward to continue seeing its benefits for the human body and brain.
Having been biohacking my mind and body long before it became fashionable, I’ve always lived by the benefits of nature’s resources to improve cognitive and physiological performance. Using my years of experience, products, and wellness practices, I’m now helping others elevate their cognitive performance to help build the life they want. I save you the time I’ve spent learning, so you can focus your time on building.
I proudly use AI to support development of my articles. As a heavily dyslexic person, writing can be a time consuming process with words often jumbled up and sentences the wrong way round. AI has become my crutch; allowing me to share the immense interest in my mind, while making content creation quicker and more accurate. AI is my benefit.
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